What is Sweet Syndrome?
Sweet syndrome, also known as acute febrile neutrophilic dermatosis (AFND), is characterized by the abrupt onset of tender, red or purplish skin lesions that can present as papules, vesicles, plaques, or nodules. The lesions are often painful and may last for days to weeks.
They are frequently found on the limbs, neck, and face but can occur anywhere on the body.
A localized variant, neutrophilic dermatosis of the hands (NDDH), is characterized by lesions on the back of the fingers, hands, and wrists.
Who is at risk for Sweet Syndrome?
Anyone can develop Sweet syndrome. It is more common in women between the ages of 30 and 50. Other risk factors include the presence of associated conditions mentioned in the Etiology section, particularly an underlying malignancy.
What are the signs and symptoms?
The abrupt onset of tender, red, or purplish skin lesions are the most common signs and symptoms. These lesions can present as papules, vesicles, plaques, or nodules and are often painful. Scale is not common, as is the case with many acute onset rashes.