What is it?
Botox is a sterile purified botulinum toxin type A, produced from fermentation of Hall strain Clostridium botulinum type A grown in a medium at one location. The product contains the neurotoxin complex, saline and human albumin.
How does it work?
Botox prevents the nerve signals from interacting with the muscle resulting in reduction of muscle activity. Typically, acetylcholine is released from nerves and is the signal that causes contraction of the muscle. Botox cleaves the SNAP-25 protein that is required for acetylcholine to interact with the muscle.
Since it is a toxin, is it harmful?
Botox has been used as a therapeutic agent since the late 1970s and has been shown to be remarkably safe. Weakness of muscles distant to the injection sites have not been reported. In the 20 years of experience in treating patients with this agent, there have been no reports of generalized weakness.
Although pregnant and lactating patients have been treated, there is lack of established data in this population.
When will I see the results?
The appearance of the lines will continue to improve over a 2 week period. At 2 weeks, the Botox will have reached its maximum effect.
How long will the results of Botox last?
The results can last anywhere from 3-6 months. Everyone is different so we cannot give an exact duration. In fact, some people have told us their lines stayed improved for up to 8 months. This is more likely to occur after repeated treatments with Botox. Also, after repeated treatments, it is possible that you may notice a resolution of creases in the skin, in the area of the Botox injections.
Some people can develop antibodies to Botox which prevents Botox from being effective.
What is hyperhidrosis?
Hyperhidrosis is a disorder characterized by excessive sweating that occurs in 1% to 3% of the population. A small dose of Botox is injected into the skin in the area of hyperhidrosis.
How is Botox used to treat hyperhidrosis?
Currently, the FDA (U.S. Food and Drug Administration) has approved the use of Botox to treat primary axillary hyperhidrosis or severe underarm sweating. Worldwide about 20 countries have approved the use of Botox in the treatment of hyperhidrosis. Botox is used to treat hyperhidrosis of the axillae and soles.